Jeff Tweedy and Josh Homme are set to make a guest appearance on American sketch comedy Portlandia when it returns for a fourth season next year.

The show, which is written and performed by Sleater-Kinney and Wild Flag singer Carrie Browstein and ex-Saturday Night Live regular Fred Armisen, takes a satirical look at the hipster neighbourhood of Portland and the various characters that inhabit the area.

Previous musical guest appearances on the show have included Jack White, Jenny Conlee and Colin Meloy of The Decemberists, Eddie Vedder, St. Vincent, Joanna Newsom and Johnny Marr. Meanwhile, as well as Tweedy and Homme, Season Four of the show has also confirmed cameos from TV on the Radio’s Tunde Adebimpe, former Guns N’ Roses bassist Duff McKagan.